Opportunity Information: Apply for NV VSR 17 001

The FY17 funding opportunity "Announcement of Anticipated Availability of Funds for Safety Research of Currently Recommended Immunizations in the United States and Other Vaccine Prototypes" (Funding Opportunity Number NV-VSR-17-001) is a discretionary cooperative agreement run by the Department of Health and Human Services (HHS) through the Office of the Assistant Secretary for Health, specifically the National Vaccine Program Office (NVPO). The core purpose is to strengthen the U.S. vaccine safety enterprise by supporting short, targeted research projects that improve how vaccine safety is monitored, studied, and communicated. The opportunity sits under the broader policy framework of the National Vaccine Plan (NVP), with a direct connection to Goal 2, which focuses on enhancing the vaccine safety system.

A central feature of this program is that it is coordinated through the Immunization Safety Task Force (ISTF), a federal coordination body led by NVPO that was formed in 2009 to align and improve vaccine safety activities across the U.S. government. The ISTF includes experts and participating components across HHS agencies such as BARDA, CDC, FDA, IHS, NIH, and HRSA, and it also involves the Department of Veterans Affairs and the Department of Defense. By bringing these partners together, the ISTF helps identify practical scientific and programmatic gaps where additional research could meaningfully improve vaccine safety surveillance and related public health work. In other words, this grant is designed to fund projects that address real-world needs identified through cross-agency coordination, rather than isolated academic questions.

The mechanism used here is a cooperative agreement, which signals that NVPO is not simply providing funds and stepping back. Instead, NVPO scientific staff are expected to have substantial involvement throughout the project in ways that go beyond typical grant oversight. That involvement includes helping shape the study design and development, providing scientific and programmatic input while the work is underway, connecting awardees to relevant vaccine safety stakeholders, maintaining frequent communication with the principal investigator and study team to review progress and plan next steps, and participating in the development of publications and public presentations that come out of the research. This structure is meant to increase the usefulness, coordination, and potential impact of the funded work, particularly for projects that are time-limited and meant to produce actionable outputs quickly.

The program encourages collaborative, interdisciplinary proposals and explicitly anticipates partnerships with institutions and organizations, including state and local public health departments and HHS Regional Offices. The intent is to generate results that can be integrated into the broader vaccine safety system, not just produce standalone findings. This opportunity is also positioned as one option within a larger ecosystem of federally supported vaccine safety research. It is described as complementary to other federal efforts such as the NIH and CDC-supported "Research to Advance Vaccine Safety" opportunities (R01/R21 mechanisms under PA-15-312 and PA-15-313). What distinguishes NV-VSR-17-001 is its emphasis on exploratory and programmatic work that can be completed within one year, making it well-suited for pilot studies, rapid assessments, method development, or targeted interventions that can be tested and evaluated on a compressed timeline.

The opportunity provides a sense of the kinds of projects NVPO has supported in the past to illustrate fit. Examples include research analyzing fever after vaccination among infants receiving their first pertussis immunization, comparing outcomes for babies born to vaccinated mothers versus unvaccinated mothers, and another project focused on developing an evidence-based intervention to reduce injection pain or the perception of pain during vaccination. These examples point to the program's practical orientation: projects can range from evaluating potential adverse events and risk factors to testing strategies that reduce negative experiences associated with vaccination, all with the larger goal of improving safety monitoring and vaccination practice.

Administratively, the opportunity was created on December 27, 2016, with an original closing date of March 27, 2017. It falls under CFDA 93.344, uses the cooperative agreement funding instrument, and is categorized under health-related funding activities. The posted award ceiling is $400,000, with an expectation of up to three awards. Eligibility is listed broadly as "Others," with the details intended to be clarified in the full eligibility section of the announcement. Overall, the program is designed to rapidly fund high-impact vaccine safety projects, while leveraging close NVPO involvement and federal stakeholder coordination to ensure the work aligns with national vaccine safety priorities and produces outputs that can be used across the immunization system.

  • The Department of Health and Human Services, Office of the Assistant Secretary for Health in the health sector is offering a public funding opportunity titled "FY17 Announcement of Anticipated Availability of Funds for Safety Research of Currently Recommended Immunizations in the United States and Other Vaccine Prototypes" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.344.
  • This funding opportunity was created on Dec 27, 2016.
  • Applicants must submit their applications by Mar 27, 2017 No Explanation. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $400,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for NV VSR 17 001

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