Opportunity Information: Apply for PAR 22 060

The Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15, Clinical Trial Not Allowed) is a National Institutes of Health (NIH) grant opportunity designed to broaden participation in NIH-funded research by supporting smaller-scale biomedical and behavioral research projects at institutions that historically receive limited NIH funding. The central idea is to help faculty at eligible schools launch or strengthen research programs while also giving undergraduate and graduate students meaningful, hands-on exposure to high-quality research. In practice, REAP is meant to build local research capacity, increase research training opportunities for students in health professional and graduate education settings, and help institutions develop a stronger, more sustainable research environment.

This funding opportunity specifically targets domestic educational institutions that award NIH-relevant baccalaureate or advanced degrees in health professions and that have not been major recipients of NIH support. Eligibility hinges on an NIH funding threshold: the institution must have received less than $6 million per year in NIH support (total costs) in at least 4 of the last 7 federal fiscal years. An important nuance in this announcement is how “college” is defined for eligibility purposes: a college is treated as a stand-alone entity rather than as a component of a larger university system, which can matter when determining whether the NIH funding threshold is met.

REAP R15 awards are intended for small-scale research projects proposed by faculty members at eligible institutions. While the program supports both basic and clinical research, the specific version of the opportunity described here does not allow clinical trials, meaning applicants must propose research that does not meet NIH’s definition of a clinical trial. Even with that restriction, the scope can still be broad across NIH-relevant topics, including mechanistic lab studies, preclinical investigations, observational or translational work that does not qualify as a clinical trial, and other biomedical or behavioral research that fits within NIH’s mission and institute priorities.

A defining feature of REAP is its explicit emphasis on student involvement and institutional development. Projects are expected to create research experiences that engage undergraduate and/or graduate students, helping them build skills, confidence, and interest in research careers. At the same time, the program aims to strengthen the overall research culture and infrastructure at the applicant institution, making it more feasible for faculty and students to participate in competitive research over the long term.

The opportunity is listed as a discretionary grant under the NIH, with the funding opportunity number PAR 22 060. The award ceiling is $375,000, indicating the maximum amount expected for an individual award under this announcement. The associated CFDA numbers span many NIH program areas, reflecting that multiple NIH institutes and centers may participate and that a wide range of scientific topics may be considered as long as they align with NIH priorities.

In terms of who can apply, the eligible applicant categories are broad and include many types of U.S.-based organizations and government entities, such as public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses) and small businesses, and various levels of government (state, county, city/township, special districts), as well as independent school districts and certain housing authorities. The announcement also explicitly highlights a range of institution types that may be eligible when they meet the program’s criteria, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, eligible federal agencies, regional organizations, tribal governments that are not federally recognized, and U.S. territories or possessions.

Restrictions on foreign participation are clear. Non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply. However, “foreign components” as defined in the NIH Grants Policy Statement are allowed, meaning a U.S. applicant organization may include certain well-justified international elements within the project when permitted by NIH policy and when they are necessary or strongly advantageous to the research aims.

Key dates included with the listing show an original closing date of 2025-01-07, and a creation date of 2022-01-10. Applicants should still verify the most current submission schedule, any subsequent due dates, and institute-specific participation details directly in the full FOA and on NIH/Grants.gov, since NIH announcements can have multiple receipt dates and can be updated over time.

Overall, REAP (R15) is best understood as an NIH mechanism meant to bring strong but less NIH-funded health professional schools and graduate schools further into the national research enterprise by funding focused, faculty-led projects that actively involve students and improve the institution’s research capacity, while keeping project scope appropriately sized for the award limits and ensuring no clinical trials are proposed under this particular announcement.

  • The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.351, 93.361, 93.837, 93.838, 93.839, 93.840, 93.846, 93.853, 93.855, 93.865, 93.866, 93.867.
  • This funding opportunity was created on 2022-01-10.
  • Applicants must submit their applications by 2025-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $375,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 22 060

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