Opportunity Information: Apply for W81XWH 22 MRP MCAA

The Department of Defense (DoD), through the Department of the Army and the U.S. Army Medical Research Acquisition Activity (USAMRAA), offered the DoD Melanoma, Mid-Career Accelerator Award (MCAA) under the Melanoma Research Program (MRP). This opportunity was designed specifically to support independent, mid-career investigators who are positioned to make high-impact contributions in melanoma research and who are ready for a funding mechanism that helps push them into recognized leadership roles within the melanoma research community. The core idea is career acceleration through meaningful, results-driven melanoma research, rather than early-stage exploration or entry-level training.

A central feature of the award is its focus on applicants who already have a track record in melanoma research and/or direct melanoma patient care. The program expects proposed projects to be strongly justified and mature enough to demonstrate feasibility. As a result, preliminary data relevant to melanoma is required, and the application must show clear logical reasoning and a sound scientific rationale. In practical terms, this means the DoD is looking for well-grounded projects with a persuasive argument for why the work should succeed, why it matters to melanoma, and why the investigator is well-positioned to deliver impactful outcomes.

The MCAA also emphasizes connection and collaboration with the FY21 MRP Melanoma Academy, aiming to strengthen the broader melanoma research network supported by the program. Awardees are encouraged to participate in Melanoma Academy activities such as networking events and seminars hosted by the Academy leadership, which is intended to create opportunities for collaboration, visibility, and cross-pollination of ideas between mid-career PIs and Melanoma Academy Scholars. Beyond encouragement, there is also a required engagement component: MCAA Principal Investigators must attend one meeting hosted by the FY21 MRP Melanoma Academy Leadership during the second year of the award to present project information or share results. This requirement reinforces the program's interest not only in funding research, but also in building an active, connected community that shares progress and lessons learned.

From an administrative standpoint, the funding opportunity number is W81XWH 22 MRP MCAA, and it falls under CFDA 12.420, categorized as Science and Technology and other Research and Development. The funding instrument types listed are Cooperative Agreement and Grant, which signals that awards could involve either more standard grant management or a cooperative arrangement with more involvement from the funding agency, depending on how the award is structured. Eligibility was listed as unrestricted, meaning it was broadly open to applicant entity types, subject to any additional eligibility language in the full announcement. The opportunity was created on June 1, 2022, with an original closing date of October 5, 2022, and the program expected to make about four awards. The notice lists an award ceiling of 0, which typically indicates the ceiling was not specified in that particular summary field rather than implying no funding, and applicants would need to rely on the full funding announcement for exact budget limits and guidance.

Overall, the MCAA is best understood as a targeted mechanism to back mid-career melanoma investigators who can show credible early evidence supporting their approach, articulate a rigorous and logical research plan, and contribute to the DoD-supported melanoma research ecosystem through active engagement with the Melanoma Academy community and formal sharing of progress in year two.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Melanoma, Mid-Career Accelerator Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Jun 01, 2022.
  • Applicants must submit their applications by Oct 05, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: DoD Melanoma, Mid-Career Accelerator Award (MCAA) - Melanoma Research Program (MRP)

What is the DoD Melanoma, Mid-Career Accelerator Award (MCAA)?

The DoD Melanoma, Mid-Career Accelerator Award (MCAA) is a funding opportunity offered through the Department of Defense (DoD), Department of the Army, and administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Melanoma Research Program (MRP). It is designed to accelerate the careers of independent, mid-career investigators by supporting meaningful, results-driven melanoma research that can propel them into recognized leadership roles in the melanoma research community.

What is the main goal of this award?

The main goal is career acceleration through high-impact melanoma research. The emphasis is on supporting investigators who are ready for a mechanism that helps move them into visible leadership positions, rather than funding early-stage exploration or entry-level training.

Who is this opportunity intended for?

This opportunity is intended for independent, mid-career investigators who are positioned to make high-impact contributions in melanoma research and are ready to expand their influence and recognition within the melanoma research community.

Does the applicant need prior melanoma experience?

Yes. A central feature of the MCAA is its focus on applicants who already have a track record in melanoma research and/or direct melanoma patient care. The program expects that applicants can demonstrate relevant experience and readiness to deliver impactful outcomes.

What kind of research projects are a good fit for the MCAA?

Projects should be strongly justified, mature enough to demonstrate feasibility, and framed around meaningful, results-driven melanoma research. The opportunity is not positioned as a mechanism for early exploratory ideas; it favors well-grounded projects with a clear scientific rationale and a persuasive argument for significance and likelihood of success.

Is preliminary data required?

Yes. Preliminary data relevant to melanoma is required. Applications are expected to include clear logical reasoning and sound scientific rationale supported by melanoma-relevant evidence.

What does the program mean by "feasible" and "mature enough" projects?

Based on the description, the DoD expects proposals to be supported by preliminary melanoma-relevant data and a rigorous scientific justification. In practical terms, the project should be developed enough that reviewers can see why the approach should work, why it matters to melanoma, and why the investigator is well-positioned to achieve impactful outcomes.

How does the MCAA relate to the FY21 MRP Melanoma Academy?

The MCAA emphasizes connection and collaboration with the FY21 MRP Melanoma Academy. The intent is to strengthen the melanoma research network supported by the program by encouraging engagement between MCAA Principal Investigators and Melanoma Academy Scholars and leadership.

Are MCAA awardees required to participate in Melanoma Academy activities?

Participation is encouraged through activities such as networking events and seminars hosted by the Melanoma Academy leadership. In addition, there is a specific required engagement component tied to the award (see the year-two meeting requirement).

What is the required engagement component during the award period?

MCAA Principal Investigators must attend one meeting hosted by the FY21 MRP Melanoma Academy Leadership during the second year of the award. At this meeting, the PI is required to present project information or share results. This requirement is meant to support active community-building and the sharing of progress and lessons learned.

When must the required meeting attendance occur?

The required meeting attendance is during the second year of the award, at a meeting hosted by the FY21 MRP Melanoma Academy Leadership.

What is the funding opportunity number for this award?

The funding opportunity number is W81XWH 22 MRP MCAA.

What CFDA number and category are associated with this opportunity?

The opportunity is listed under CFDA 12.420 and categorized as Science and Technology and other Research and Development.

What funding instrument types are used for this opportunity?

The listed funding instrument types are Cooperative Agreement and Grant. This indicates that awards could be structured either as a standard grant or as a cooperative agreement, which typically includes a higher level of involvement from the funding agency depending on how the award is set up.

What does "eligibility: unrestricted" mean here?

The eligibility was listed as unrestricted, meaning it was broadly open to applicant entity types, subject to any additional eligibility language in the full announcement.

How many awards were expected to be made?

The program expected to make about four awards.

What were the key dates for this opportunity?

The opportunity was created on June 1, 2022, and the original closing date was October 5, 2022.

Is there a stated maximum award amount (award ceiling)?

The notice lists an award ceiling of 0. In this context, that typically indicates the ceiling was not specified in that particular summary field rather than implying no funding. Applicants would need to consult the full funding announcement for exact budget limits and detailed guidance.

What does this program prioritize in an application?

Based on the description, the MCAA prioritizes: (1) a demonstrated track record in melanoma research and/or melanoma patient care, (2) a mature and feasible project supported by preliminary melanoma-relevant data, (3) clear logical reasoning and a sound scientific rationale, (4) a persuasive case for why the work matters to melanoma and is likely to succeed, and (5) engagement with the FY21 MRP Melanoma Academy community, including a required year-two presentation.

Is this award meant for training or early career development?

No. The MCAA is framed as a mid-career accelerator focused on career advancement through results-driven research, rather than early-stage exploration or entry-level training.

What is USAMRAA's role in this opportunity?

USAMRAA (the U.S. Army Medical Research Acquisition Activity) is the administering organization through which the Department of the Army and DoD offered this award under the Melanoma Research Program.

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