Opportunity Information: Apply for HT942525AZRPTRDA
The Alzheimer’s Research Program Transforming Diagnosis Award (Funding Opportunity Number HT942525AZRPTRDA) is a discretionary grant opportunity from the Department of the Army, administered through USAMRAA, focused on science and technology research and development (CFDA 12.420). The core purpose of this award is to support solutions-oriented research that can meaningfully improve how Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD) are diagnosed and how patient prognosis is determined. In practical terms, the program is looking for projects aimed at making diagnosis and prognosis more accurate, more timely, and more useful for clinical decision-making and patient outcomes, rather than purely exploratory work without a clear path to impact.
A key structural feature of this opportunity is the option to propose a project with multiple principal investigators through the Career Initiation or Transition (CIT) Partnership Option. Under this arrangement, only the initiating PI submits the pre-application, but each PI involved must submit a full application. Applicants should pay close attention to the dependency created by this linked submission approach: if the initiating or partnering application is rejected or is administratively withdrawn, the government notes that all associated applications tied to the same research project may also be withdrawn. That makes coordination, consistency across submissions, and compliance with application requirements especially important for teams using the partnership option.
The opportunity also makes collaboration with the community a requirement, not an optional add-on. While the notice does not define the exact model, this typically implies meaningful engagement with affected communities, patients, caregivers, advocacy groups, or community-based organizations, with collaboration that influences the project design, conduct, and/or dissemination of results. Beyond collaboration, the program strongly encourages applicants to leverage existing resources and established cohorts. This is particularly emphasized for resources that address critical health challenges, suggesting that proposals that build on well-characterized participant cohorts, existing datasets, biobanks, clinical networks, or ongoing longitudinal studies may be viewed favorably because they can accelerate progress and improve generalizability without reinventing infrastructure.
Administrative details provided include an unrestricted eligibility statement (meaning there are no applicant-type limits listed in the summary), an original closing date of 2025-08-29, and an expected number of awards of 2. The award ceiling is not specified in the provided summary, so prospective applicants would need to consult the full announcement for budget limits, performance period, cost share (if any), and any constraints on allowable costs. Overall, this funding opportunity is geared toward high-impact, practically oriented AD/ADRD diagnostic and prognostic advances, with built-in expectations for community partnership and a preference for smart use of existing cohorts and resources, and it offers a formal pathway for multi-PI submissions through the CIT partnership mechanism.Apply for HT942525AZRPTRDA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Alzheimer’s Research Program Transforming Diagnosis Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2025-04-18.
- Applicants must submit their applications by 2025-08-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted.
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Frequently Asked Questions (FAQs)
What is the Alzheimer’s Research Program Transforming Diagnosis Award?
It is a discretionary grant opportunity titled the Alzheimer’s Research Program Transforming Diagnosis Award. The funding opportunity number is HT942525AZRPTRDA. It is offered by the Department of the Army and administered through USAMRAA, and it falls under CFDA 12.420 (science and technology research and development).
What is the main goal of this award?
The core purpose is to support solutions-oriented research that can meaningfully improve how Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD) are diagnosed and how patient prognosis is determined. The emphasis is on practical improvements that make diagnosis and prognosis more accurate, more timely, and more useful for clinical decision-making and patient outcomes.
What kinds of projects does the program seem to prioritize?
Based on the summary provided, the program is looking for projects that have a clear path to impact in diagnosis and prognosis for AD/ADRD. The opportunity description highlights improvements in accuracy, timeliness, and clinical usefulness, rather than projects that are purely exploratory without a clear route to real-world benefit.
Does the opportunity allow multiple Principal Investigators (PIs)?
Yes. The opportunity includes an option to propose a project with multiple principal investigators through the Career Initiation or Transition (CIT) Partnership Option.
How does the CIT Partnership Option work at the pre-application stage?
Under the CIT Partnership Option, only the initiating PI submits the pre-application.
How does the CIT Partnership Option work at the full application stage?
Each PI involved in the partnership must submit a full application. This creates a linked or dependent submission structure among the PIs tied to the same research project.
What is the risk of linked submissions under the CIT Partnership Option?
The government notes that if the initiating or partnering application is rejected or is administratively withdrawn, all associated applications tied to the same research project may also be withdrawn. Teams using this option should coordinate closely to keep submissions consistent and compliant.
Is community collaboration optional or required?
Community collaboration is described as a requirement, not an optional add-on. The summary indicates that applicants are expected to collaborate with the community as part of the project.
What does “community collaboration” mean for this opportunity?
The notice summary does not define a single required model. However, it indicates meaningful engagement with affected communities, such as patients, caregivers, advocacy groups, or community-based organizations, where the collaboration influences the project design, conduct, and/or dissemination of results.
Does the program encourage use of existing cohorts or resources?
Yes. The program strongly encourages applicants to leverage existing resources and established cohorts. Examples referenced in the summary include well-characterized participant cohorts, existing datasets, biobanks, clinical networks, or ongoing longitudinal studies.
Why does leveraging existing resources matter for this award?
The summary suggests that building on established cohorts and resources may be viewed favorably because it can accelerate progress and improve generalizability without recreating infrastructure from scratch.
Who is eligible to apply?
The eligibility statement is described as unrestricted in the provided summary, meaning no applicant-type limits are listed there. Applicants should still confirm details in the full announcement.
What is the application deadline?
The original closing date listed in the summary is 2025-08-29.
How many awards are expected?
The expected number of awards is 2, according to the summary provided.
Is there a maximum award amount (award ceiling)?
The award ceiling is not specified in the provided summary. Prospective applicants would need to consult the full announcement for budget limits and any related constraints.
Does the summary mention cost share requirements?
No. The summary states that applicants would need to consult the full announcement for cost share (if any), as well as other budget and period-of-performance details.
Does the summary specify the performance period?
No. The performance period is not included in the provided summary and would need to be confirmed in the full announcement.
Does the summary specify allowable or unallowable costs?
No. Allowable costs and any spending constraints are not included in the provided summary and would need to be checked in the full announcement.
What agency administers this opportunity?
The opportunity is from the Department of the Army and is administered through USAMRAA.
What disease area does this award focus on?
The focus is Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD), specifically improving diagnosis and prognosis.
Is the program more interested in clinical usefulness than exploratory research?
Yes. The summary emphasizes solutions-oriented work that improves clinical decision-making and patient outcomes, and it contrasts that with purely exploratory work that lacks a clear path to impact.
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