Alzheimer’s Research Program Transforming Diagnosis Award | HT942525AZRPTRDA

Opportunity Information: Apply for HT942525AZRPTRDA

The Alzheimer’s Research Program Transforming Diagnosis Award (Funding Opportunity Number HT942525AZRPTRDA) is a discretionary grant opportunity from the Department of the Army, administered through USAMRAA, focused on science and technology research and development (CFDA 12.420). The core purpose of this award is to support solutions-oriented research that can meaningfully improve how Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD) are diagnosed and how patient prognosis is determined. In practical terms, the program is looking for projects aimed at making diagnosis and prognosis more accurate, more timely, and more useful for clinical decision-making and patient outcomes, rather than purely exploratory work without a clear path to impact.

A key structural feature of this opportunity is the option to propose a project with multiple principal investigators through the Career Initiation or Transition (CIT) Partnership Option. Under this arrangement, only the initiating PI submits the pre-application, but each PI involved must submit a full application. Applicants should pay close attention to the dependency created by this linked submission approach: if the initiating or partnering application is rejected or is administratively withdrawn, the government notes that all associated applications tied to the same research project may also be withdrawn. That makes coordination, consistency across submissions, and compliance with application requirements especially important for teams using the partnership option.

The opportunity also makes collaboration with the community a requirement, not an optional add-on. While the notice does not define the exact model, this typically implies meaningful engagement with affected communities, patients, caregivers, advocacy groups, or community-based organizations, with collaboration that influences the project design, conduct, and/or dissemination of results. Beyond collaboration, the program strongly encourages applicants to leverage existing resources and established cohorts. This is particularly emphasized for resources that address critical health challenges, suggesting that proposals that build on well-characterized participant cohorts, existing datasets, biobanks, clinical networks, or ongoing longitudinal studies may be viewed favorably because they can accelerate progress and improve generalizability without reinventing infrastructure.

Administrative details provided include an unrestricted eligibility statement (meaning there are no applicant-type limits listed in the summary), an original closing date of 2025-08-29, and an expected number of awards of 2. The award ceiling is not specified in the provided summary, so prospective applicants would need to consult the full announcement for budget limits, performance period, cost share (if any), and any constraints on allowable costs. Overall, this funding opportunity is geared toward high-impact, practically oriented AD/ADRD diagnostic and prognostic advances, with built-in expectations for community partnership and a preference for smart use of existing cohorts and resources, and it offers a formal pathway for multi-PI submissions through the CIT partnership mechanism.

• The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Alzheimer’s Research Program Transforming Diagnosis Award" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
• This funding opportunity was created on 2025-04-18.
• Applicants must submit their applications by 2025-08-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 2 candidate(s).
• Eligible applicants include: Unrestricted.

Apply for HT942525AZRPTRDA

[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal: